Activity and Cancer Survivorship Exercise Pilot

University of Iowa

Status: Active, not recruiting

Conditions: Endometrial Cancer

Treatments: Other: Functional fitness following home-based comprehensive exercise program

Study type: Interventional

Funder types: Other

Identifiers

NCT07283029

202212082

Details and patient eligibility

About

This early phase I clinical trial measures the changes in functional fitness following home-based comprehensive exercise program in patients who have endometrial cancer who have completed treatment. Endometrial cancer is an increasingly common diagnosis, with health and quality of life concerns persisting after the active cancer treatment period. Exercise in cancer survivors has the potential to reduce the risk of death by improving cardiovascular fitness, quality of life, strength, longevity, and independence. A home-based exercise programs may be a feasible approach for exercise programming in patients who have endometrial cancer who have completed treatment.

Enrollment: 10 patients

Sex: Female

Ages: 18 to 74 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Willing to provide written informed consent
• Willing to comply with all study procedures and be available for the duration of the study
• Fluent in spoken and written English
• Women 18-74 years of age
• Documented diagnosis of type I, stage I-IIIc endometrial cancer within the past 5 years
• Completion of current treatment for endometrial cancer
• Technology access (cellphone with data, broadband internet, WiFi) for tele coaching
• Pass the Physical Activity Readiness Questionnaire (PAR-Q)

Exclusion criteria

• Absolute contraindications to exercise (i.e., acute myocardial infarction, severe orthopedic or musculoskeletal limitations
• Have evidence of recurrent or metastatic disease
• Are currently performing resistance training >= 2 days per week
• Are currently exceeding 150 minutes of at least moderate intensity activity per week
• Report of chest pain, shortness of breath, fainting, or angina pectoris
• Have physical disability that would limit range of motion through exercises such as sitting, standing and inability to walk one block
• Plans to move from the area
• Enrolled in another clinical trial or has used of any investigational drugs, biologics, or devices within 30 days prior to randomization
• Women who are pregnant or breast-feeding
• Not suitable for study participation due to other reasons at the discretion of the investigator
• Failing the Physical Activity Readiness Questionnaire

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

10 participants in 1 patient group

Exercise Intervention

Experimental group

Treatment:

Other: Functional fitness following home-based comprehensive exercise program