Acupressure Wristbands for GLP-1RA Related Nausea

Florencia Ziemke

Status: Active, not recruiting

Conditions: Nausea

Treatments: Device: SeaBand

Study type: Interventional

Funder types: Other

Identifiers

NCT06939517

STU25020070_evexiamed

Details and patient eligibility

About

Nausea is a common side effect of GLP-1RA medications used for treatment of Type 2 diabetes mellitus and obesity. Current recommendations for nausea relief include the use of dietary changes and prescription anti-emetics. Acupressure wristbands Sea-Band are FDA cleared for nausea relief in other indications such as motion sickness, morning sickness in pregnancy, post-operative nausea, chemotherapy associated nausea. We hypothesized that acupressure wristbands could alleviate nausea in persons taking GLP-1RA.

Full description

Nausea is the most commonly reported side effect of the class of drugs collectively known as glucagon like peptide-1 receptor agonists (GLP-1RA). GLP-1RAs are FDA approved to treat Type 2 diabetes mellitus (T2DM) and Obesity. Sea-Band is an FDA-cleared set of drug-free elastic wristbands used for nausea relief in several indications including motion sickness, morning sickness in pregnancy, post-operative nausea, chemotherapy associated nausea in persons ages 3 years old and up. The elastic wristbands have a plastic skin facing knob that apples pressure to an acupressure point called pericardium 6 (P6) located below the crease of the wrist. We hypothesize that Sea-Band can alleviate nausea in persons taking GLP-1RA. Participants on GLP-1RA medication with nausea were offered a set of Acupressure wristbands, and followed for four weeks. Weekly touch points assessed the response to nausea relief of the bands. Eligibility for the study included Adults taking GLP-1RA experiencing nausea.

Enrollment: 35 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults taking GLp-1RA with nausea

Exclusion criteria

• Adults on GLP-1RA without nausea
• Uncontrolled GERD
• Hx of Gastroparesis
• Other nausea related conditions such as vertigo
• History of chronic use of antiemetic medication for other reasons

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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35 participants in 1 patient group

Acupressure wristband

Experimental group

Description:

Study arm using acupressure wristband for nausea relief associated to GLP-1

Treatment:

Device: SeaBand