Acupuncture for Symptom Control in Hematopoietic Stem Cell Transplantation Patients

Memorial Sloan Kettering Cancer Center (MSK)

Status: Completed

Conditions: Multiple Myeloma

Treatments: Procedure: Sham acupuncture; Procedure: Acupuncture

Study type: Interventional

Funder types: Other

Identifiers

NCT01811862

13-038

Details and patient eligibility

About

This is a prospective randomized controlled trial to obtain preliminary data for the design of a future definitive efficacy study. A randomized controlled trial is needed because comparison to historical data would be biased. The investigators will use sham acupuncture as the control to account for effect from attention from and interaction with the therapist.

Enrollment: 63 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 21 or above (those age below 21 are usually treated in the Pediatric Transplant Service)
• Diagnosis of multiple myeloma
• Scheduled to receive conditioning chemotherapy followed by upfront or salvage autologous peripheral blood hematopoietic stem cell transplantation

Exclusion criteria

• Absolute neutrophil count less than 200/microliter
• Platelet count less than 20,000/microliter
• Acupuncture treatment in the preceding 4 weeks prior to Day 1

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

63 participants in 2 patient groups

Acupuncture

Experimental group

Description:

Acupuncture treatment once daily inpatient for 5 consecutive days starting at on the day after chemotherapy plus usual pre- and post-transplantation care.

Treatment:

Procedure: Acupuncture

Sham acupuncture

Sham Comparator group

Description:

Sham acupuncture once daily inpatient for 5 consecutive days starting at on the day after chemotherapy plus usual pre- and post-transplantation care.

Treatment:

Procedure: Sham acupuncture