Acupuncture in Myasthenia Gravis (AcuMG)

HealthPartners Institute

Status: Completed

Conditions: Myasthenia Gravis

Treatments: Other: Acupuncture

Study type: Interventional

Funder types: Other

Identifiers

NCT05230082

A21-197

Details and patient eligibility

About

The purpose of the study is to determine the effect acupuncture treatment on individuals with a diagnosis of Myasthenia Gravis (MG). A total of 20 people with MG will be enrolled in this study to receive acupuncture treatment 2 times a week for 12 weeks. Participants will be randomized into two groups: 1) Immediate start and 2) Delayed start (12 weeks). The delayed start group will act as a control group for the first 12 weeks, but then receive acupuncture treatment for 12 weeks. It is hypothesized that patients with MG who receive acupuncture treatment will have improved quality of life and activities of daily living compared to no treatment.

Enrollment: 24 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ability to provide and provision of signed and dated informed consent form
• Age 18-80
• Diagnosis of MG

Exclusion criteria

• Non-English speaking
• Participation in acupuncture treatment outside of the study, while enrolled
• History of any other serious neurological, psychiatric, chronic pain disorders, or seizures
• History of bleeding diathesis, other bleeding disorders, or syncope with needle puncture
• History of cardiac arrhythmia or current pacemaker, neurostimulator, or other implanted stimulation device
• Recent or active substance use disorder
• Women who are currently pregnant, lactating, or planning to become pregnant during the study
• Any other medical conditions that could affect their ability to participate in acupuncture treatments for the study duration (as determined by study investigators)
• Active participation or past participation ≤3 months in any other interventional study.
• Unwilling to participate in all study related activities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

Immediate Start

Experimental group

Description:

Patients will receive acupuncture treatment two times per week for 12 weeks.

Treatment:

Other: Acupuncture

Delayed start

Active Comparator group

Description:

Patients will act as control group for the first 12 weeks then will receive acupuncture treatment two times per week for 12 weeks.

Treatment:

Other: Acupuncture