Acute Cardiovascular Responses and Chronic Adaptations of Strength Exercise in Intermittent Claudication Patients

University of Pernambuco

Status: Completed

Conditions: Peripheral Artery Disease; Intermittent Claudication

Treatments: Behavioral: Resistance training; Behavioral: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT02778568

RMR2013FCPE MOVED

Details and patient eligibility

About

The aim of this study was to analyze the effects of resistance exercise and training on cardiovascular function of peripheral artery disease patients.

Full description

Several studies have shown that strength training can promote important benefits for the cardiovascular system in healthy subjects and patients with chronic diseases. However, the effects of resistance exercise on cardiovascular function in intermittent claudication patients are unclear. In addition, it also do not know the chronic effects on cardiovascular function in these patients.

Enrollment: 30 patients

Sex: All

Ages: 50 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Had a graded treadmill test that was limited by claudication (2 minutes)
• Had an ankle brachial index <0.90
• Had systolic blood pressure ,160 mmHg and/or diastolic blood pressure,105 mmHg
• Were not performing any regular exercise program
• Were not using antihypertensive medications affecting the heart rate (e.g., b-blockers and nondihydropyridine calcium channel blockers)
• Were nonobese
• Individuals who have not undergone bypass surgery or angioplasty least one year ago

Exclusion criteria

• Had no symptoms related to myocardial ischemia during the treadmill test
• Amputation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Resistance Training

Experimental group

Description:

Patients performed resistance exercises

Treatment:

Behavioral: Resistance training

Control

Active Comparator group

Description:

Patients who performed flexibility exercise

Treatment:

Behavioral: Control