Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study

Mansoura University

Status: Unknown

Conditions: Acute Cholecystitis

Treatments: Procedure: Early cholecystectomy; Procedure: Delayed cholecystectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT02130245

Early cholecystectomy

Details and patient eligibility

About

The best management of the acute cholecystitis is to do laparoscopic cholecystectomy. The hypothesis is that to do it as an early intervention after patient admission is better than delayed cholecystectomy regarding the hospital stay, interval for antibiotic, the easiness of the operative maneuver reflected by operative time, conversion and intraoperative complications.

Full description

Doing laparoscopic cholecystectomy for patients with acute cholecystitis as an early intervention after patient admission ( first group) or to do it after a while of treatment and conservation as a delayed cholecystectomy (second group) points of study include the hospital stay, interval for antibiotic, the easiness of the operative maneuver reflected by operative time, conversion and intraoperative complications.

Enrollment: 600 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Proved acute cholecystitis clinical, radiologic

Exclusion criteria

• Evidence of peritonitis
• ASA III or IV
• Previous upper abdominal surgery
• Pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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600 participants in 2 patient groups

Early cholecystectomy

Active Comparator group

Description:

Laparoscopic cholecystectomy well be done after the immediate admission

Treatment:

Procedure: Early cholecystectomy

Delayed cholecystectomy

Active Comparator group

Description:

Laparoscopic cholecystectomy after a period of conservative treatment

Treatment:

Procedure: Delayed cholecystectomy