Acute Colon Resection Versus Bridge to Colon Surgery With Stent or Stoma (ACBC)

Skane University Hospital

Status: Enrolling

Conditions: Colon Cancer

Treatments: Procedure: Bridge to Surgery (stent or stoma)

Study type: Observational

Funder types: Other

Identifiers

NCT04450758

Skane University Hospital

Details and patient eligibility

About

P) patients with acute obstructive colon cancer I) resection or bridge to surgery with stent or stoma C) emergency procedure O ) morbidity and mortality within 30 days, 90 day mortality and 3 & 5 years overall survival

Full description

The aim of this prospective observational study is to evaluate primary resection for malignant obstruction of the colon compared to only decompression as first intervention regarding postoperative outcomes. We hypothesize that patients with malignant obstruction benefit from avoidance of emergency cancer resection, by a two-stage procedure, with decompression by a stoma or stent as first intervention, leading to decreased short-term morbidity and mortality and improved long-term oncological outcome.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >18 years
• Symptomatic large bowel obstruction requiring acute intervention
• CT-verified colon obstruction due to colon cancer independent of presence of metastases
• Informed consent

Exclusion criteria

• Colonic perforation or bleeding
• Colonic obstruction of other origin than colon cancer
• Palliative situation

Trial design

1,000 participants in 2 patient groups

resection

Description:

Patients who present with obstruction due to colon cancer with a need for urgent intervention who are treated with acute resection.

bridge to sugery

Description:

Patients who present with obstruction due to colon cancer with a need for urgent intervention who are treated with bridge to surgery i.e. either stent or stoma and resection later on.

Treatment:

Procedure: Bridge to Surgery (stent or stoma)