Acute Cycling on Executive Control (ACE)

Western University, Canada

Status: Completed

Conditions: Physical Activity

Treatments: Behavioral: High-Intensity Cycling; Behavioral: Light-Intensity Cycling; Behavioral: Moderate-Intensity Cycling; Behavioral: Sitting

Study type: Interventional

Funder types: Other

Identifiers

NCT03499977

PA and Executive Functioning

Details and patient eligibility

About

This study will examine whether 10-minute bouts of cycling at various intensities will impact executive functioning (i.e., cognitive ability) as assessed by the antisaccade (AS) task through a total of five visits. An antisaccade is a rapid eye movement away from a visual target. The ability to suppress making an eye movement towards a visual target gauges inhibitory control (i.e., a domain of executive functioning). In the initial visit, participants' exercise capacity will be assessed through a maximal effort cycling test. Intensities for the cycling bouts (i.e., high, moderate, low) in subsequent sessions will be based upon this maximal effort cycling test. In visits 2 through 5, participants will complete an AS task, followed by a 10-minute bout of cycling, and then complete the AS task again. The order of cycling intensities will be randomized between participants. Differences in the AS task (i.e., reaction time and accuracy) will be compared between and within cycling conditions.

Enrollment: 20 patients

Sex: All

Ages: 18 to 64 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Able to read, write and understand English
• Full time student enrolled at Western University
• Able to perform a ten-minute exercise task at a light intensity without health implications
• Have email or phone number for contacting purposes

Exclusion criteria

• Do not have a medical condition that prevents you from exercise (e.g. heart attack in the past year, heart disease, irregular heartbeat, etc.)
• Do not have history of eye injury or neurological impairment
• Do not have an orthopaedic limitation
• Are not pregnant

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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20 participants in 4 patient groups

Sitting

Experimental group

Description:

The participant will be asked to sit for 10 min (not increasing their heart rate) then do the anti-saccade task

Treatment:

Behavioral: Sitting

Low-Intensity Cycling

Experimental group

Description:

Participant will be asked to cycle for 10 min (\<40% VO2R) and then perform the anti-saccade task

Treatment:

Behavioral: Light-Intensity Cycling

Moderate-Intensity Cycling

Experimental group

Description:

The participant will be asked to do 10 min of cycling (40-59% VO2R) followed but the anti-saccade task

Treatment:

Behavioral: Moderate-Intensity Cycling

High-Intensity Cycling

Experimental group

Description:

The participant will be asked to do 10 min of cycling (60%-84% VO2R) followed but the anti-saccade task

Treatment:

Behavioral: High-Intensity Cycling