Acute Effect of MMT Peel Powder on Glycemic Response, Satiety, and Food Intake in Adults at Risk for Type 2 Diabetes

Universiti Sultan Zainal Abidin

Status: Completed

Conditions: At Risk of Type 2 Diabetes Mellitus

Treatments: Other: Formulation 3; Other: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT05298111

RCTOYQ

Details and patient eligibility

About

Open-label, randomised, placebo-controlled, crossover study with two intervention arms. The study was conducted in 30 respondents and the primary objective is to show an improved glycemic response after Melon Manis Terengganu (MMT) peel powder consumption in people at risk of type 2 diabetes.

Full description

The main aim of the study is to investigate the acute effect of MMT peel powder on glycemic response in people at risk of type 2 diabetes. Besides, the acute effect of MMT peel powder on perceived satiety and energy intake were explored.

Enrollment: 36 patients

Sex: All

Ages: 18 to 59 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Modified Finnish Type 2 Diabetes Risk Assessment Tool (FINDRISC) score ≥ 4
• Capillary fasting blood glucose (FBG) < 7.0 mmol/L
• Malaysian
• Live, work or study in Kuala Nerus, Terengganu
• Both gender
• Age 18 to 59 years old
• Non-smoker
• Those taking supplement agree to undergo washout period of one week

Exclusion criteria

• Had clinical history of type 2 diabetes mellitus (T2DM)
• Capillary FBG ≥ 7.0 mmol/L
• Take oral antidiabetic agents
• Participate in other weight management programme or interventional research
• On a prescribed medical diet
• GI illnesses or conditions
• Allergy or sensitivity to study products
• Pregnant, currently breastfeeding, or planning to become pregnant
• On dietary restrictions
• Smoker

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

36 participants in 2 patient groups, including a placebo group

Formulation 3

Active Comparator group

Description:

Formulated MMT peel powder (provide 5 g dietary fiber per day)

Treatment:

Other: Formulation 3

Control

Placebo Comparator group

Description:

Glucose

Treatment:

Other: Control