Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects

Aarhus University Hospital

Status: Completed

Conditions: Inflammation; Obesity; Postprandial Lipemia; Atherosclerosis; Postprandial Incretins

Treatments: Dietary Supplement: Whey Isolate; Dietary Supplement: Gluten; Dietary Supplement: Caseine; Dietary Supplement: Cod

Study type: Interventional

Funder types: Other

Identifiers

NCT00863564

CERN-PPL-JHJ-5a

Details and patient eligibility

About

The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.

Hypothesis: Certain dietary proteins reduce the amount of fat circulating in the blood stream following a fat rich meal. The effect is dependant of both the quality and the quantity of protein ingested.

Enrollment: 12 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI > 30 kg/m2 & < 45 kg/m2

Exclusion criteria

• Diabetes
• Lipid lowering drugs
• Liver-, Kidney- and/or Heart Disease
• Serious Hypertension (160/110)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

---

12 participants in 4 patient groups

Whey Isolate

Active Comparator group

Treatment:

Dietary Supplement: Whey Isolate

Caseine

Active Comparator group

Treatment:

Dietary Supplement: Caseine

Cod

Active Comparator group

Treatment:

Dietary Supplement: Cod

Gluten

Active Comparator group

Treatment:

Dietary Supplement: Gluten