Acute Effects of Exercise at Different Temperatures in Allergic Rhinitis Patient

Chulalongkorn University

Status: Completed

Conditions: Allergic Rhinitis

Treatments: Other: Cycling exercise in room temperature at 34 degree Celsius.; Other: Cycling exercise in room temperature at 25 degree Celsius.

Study type: Interventional

Funder types: Other

Identifiers

NCT05870644

EX PHYSIO SPSC 6

Details and patient eligibility

About

The purpose of this study was to determine the effects of exercise at different temperatures on nasal blood flow and symptoms in allergic rhinitis patients.

Full description

Fifteen patients with allergic rhinitis aged between 18 and 35 years who had a positive skin prick test to house dust mite (D. pteronyssinus). The experiment was a crossover design in which each participant was given aerobic exercise by ergometer in two difference temperatures room : 25 degree celsius and 34 degree celsius. Rhinitis symptoms, nasal blood flow, heart rate, and oxygen saturation were measured before, during exercise at 15, 30, and 45 minutes, and after exercise at 0, 15 and 30 minutes in each temperature. Moreover, blood pressure, peak nasal inspiratory flow, pulmonary functions, respiratory muscle strength, and fractional exhaled nitric oxide were measured before and after exercise at 0, 15 and 30 minutes in each temperature.

Enrollment: 15 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects had a clinical history of persistent rhinitis, and had positive skin prick test to house dust mite (D. pteronyssinus)
• Persistent allergic rhinitis
• Subjects with known asthma, chronic rhinosinusitis, Lung cancer and Emphysema diseases were excluded.
• BMI 18.5 - 24.9 kg/m2
• Subjects will ask to abstain from taking antihistamine for at least 5 days, leukotriene receptor antagonist for at least 1 week, and nasal steroids for at least 2 weeks prior to the start of the experiment.
• Subjects will ask to abstain from taking any form of dietary supplement during the experiment.
• Subjects had no exercise training program (not exercise regularly or not exercise for 30 minutes or more at least 3 times per week during the past 6 months)

Exclusion criteria

• Accident that are unable to continue the research, such as accidental injury or illness, etc.
• Participants did not voluntarily participate.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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15 participants in 2 patient groups

Exercise in room temperature at 25 degree Celsius.

Experimental group

Description:

The participants received a moderate exercise program of cycling at moderate intensity (50-60% HRR) for 60 minutes in room temperature at 25 degree Celsius.

Treatment:

Other: Cycling exercise in room temperature at 25 degree Celsius.

Exercise in room temperature at 34 degree Celsius.

Experimental group

Description:

The participants received a moderate exercise program of cycling at moderate intensity (50-60% HRR) for 60 minutes in room temperature at 34 degree Celsius.

Treatment:

Other: Cycling exercise in room temperature at 34 degree Celsius.