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Acute Effects of Inspiratory Muscle Training at Different Intensities in Healthy People

D

Dokuz Eylül University (DEU)

Status

Completed

Conditions

Healthy

Treatments

Other: Diaphragmatic breathing
Device: Inspiratory muscle training

Study type

Interventional

Funder types

Other

Identifiers

NCT03788356
2018/14-16

Details and patient eligibility

About

At least 30 volunteers will be included in the study. After questioning the demographic and clinical information of the participants, dyspnea perception, respiratory functions, respiratory muscle strength, heart rate variability, arterial stiffness, and blood pressure and physical activity levels will be evaluated. Inspiratory muscle training will be done for 15 minutes with an electronic device. Respiratory training will be applied at three different concentrations with 10%, 30% and 60% of maximal inspiratory pressure. Heart rate variability, arterial stiffness, and blood pressure measurements will be repeated after inspiratory muscle training sessions at different intensities.

Full description

Cardiovascular diseases are the leading cause of mortality in developed and developing countries and constitute a significant morbidity burden for life. Cardiovascular diseases risk factors include obesity, lipid profile, unhealthy diet, sedentary lifestyle, high blood pressure, increased arteriosclerosis.

Although aerobic exercise is recommended as exercise modality to reduce cardiovascular risk, the effects of resistant exercise on cardiovascular health are not clear. In addition, regular aerobic and resistant exercise regulate cardiac autonomic function.

Inspiratory muscle training is a time-efficient, well-tolerated and safe approach for both healthy people and people with chronic diseases. Long-term inspiratory muscle training has been shown to increase respiratory muscle strength and decrease blood pressure in healthy individuals. One-session inspiratory muscle training has been shown to improve autonomic function in smokers and older individuals. However, the effects of different intensities of inspiratory muscle training on blood pressure, autonomic function, and arterial stiffness in healthy young people are not fully understood. For these reasons, the aim of the study is to investigate the acute effects of inspiratory muscle training at different intensities in healthy people.

At least 30 volunteers will be included in the study. After questioning the demographic and clinical information of the participants, dyspnea perception, respiratory functions, respiratory muscle strength, heart rate variability, arterial stiffness, and blood pressure and physical activity levels will be evaluated. Inspiratory muscle training will be done for 15 minutes with an electronic device. Respiratory training will be applied at three different concentrations with 10%, 30% and 60% of maximal inspiratory pressure. Heart rate variability, arterial stiffness, and blood pressure measurements will be repeated after inspiratory muscle training sessions at different intensities.

Enrollment

36 patients

Sex

All

Ages

18 to 25 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy People

Exclusion criteria

  • Body mass index (BMI) > 30 kg/m²
  • Smoking
  • The presence of exercise habit
  • Medication use
  • Neurological, cardiovascular or respiratory disorders

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

36 participants in 4 patient groups

Diaphragmatic breathing
Experimental group
Description:
Diaphragmatic breathing exercise for 15 minutes.
Treatment:
Other: Diaphragmatic breathing
10% inspiratory muscle training
Experimental group
Description:
Inspiratory muscle training at 10% intensity of maximal inspiratory pressure for 15 minutes
Treatment:
Device: Inspiratory muscle training
30% inspiratory muscle training
Experimental group
Description:
Inspiratory muscle training at 30% intensity of maximal inspiratory pressure for 15 minutes
Treatment:
Device: Inspiratory muscle training
60% inspiratory muscle training
Experimental group
Description:
Inspiratory muscle training at 60% intensity of maximal inspiratory pressure for 15 minutes
Treatment:
Device: Inspiratory muscle training

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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