Acute Effects of Moderate Versus High Intensity Exercise on Insulin Sensitivity in Gestational Diabetes Mellitus (GDMakutt)

Norwegian University of Science and Technology

Status: Terminated

Conditions: Diabetes, Gestational

Treatments: Behavioral: exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01961401

2012/1021

Details and patient eligibility

About

Exercise training is recognized as effective in preventing and treating many chronic metabolic disorders (1), and long-term exercise programmes have similar effects on glucose control as long-term drug or insulin therapy in type 2 diabetic patients (2). The precise intensity and volume of aerobic exercise needed to produce the most wanted effects on targeted risk factors for subjects at risk of/with established type 2 diabetes, is still uncertain. In this study the investigators will investigate the acute effects of a single bout of moderate versus high intensity exercise on insulin sensitivity in pregnant women with and without gestational diabetes mellitus (GDM). The investigators think that very short bouts of high intensity exercise can be a way to reduce blood glucose in these women.

Enrollment: 9 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• pregnant
• Gestational diabetes mellitus or normal glucose tolerance
• able to exercise

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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9 participants in 3 patient groups

High intensity exercise

Experimental group

Description:

High intensity, short duration exercise on bike

Treatment:

Behavioral: exercise

Moderate exercise

Experimental group

Description:

Moderate intensity exercise training on bike

Treatment:

Behavioral: exercise

No exercise

No Intervention group

Description:

No exercise, resting in the lab