Acute Effects of Various Aerobic Exercise in Allergic Rhinitis.

Chulalongkorn University

Status: Completed

Conditions: Allergic Rhinitis

Treatments: Other: Cycling; Other: Running; Other: Swimming

Study type: Interventional

Funder types: Other

Identifiers

NCT05707611

EX PHYSIO SPSC 3

Details and patient eligibility

About

This study was to investigate the comparison among acute effects of various aerobic exercise on symptoms in allergic rhinitis patients.

Full description

Fifteen patients with allergic rhinitis aged 18 - 45 years old. The experiment was a crossover design in which each participant was given three types of exercise: running, cycling, and swimming. The participant perform moderate intensity exercise 30 minutes/time. Physiological variables, lung function variables, allergic rhinitis symptoms variables, and cytokines level in nasal secretion variables were analyzed during pre-and post-exercise. The dependent variables between pre-test and post-test were analyzed by a paired t-test. The dependent variables between groups were analyzed by independent t-test. One way repeated measures ANOVA was used to compare the variables among exercise. Differences were considered to be significant at p < 0.05.

Enrollment: 15 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of allergic rhinitis diseases
• Clinical symptoms of persistent rhinitis (nasal congestion, sneeze, nasal itching, and running nose) for more than 4 days per week.
• Positive skin prick test (wheal diameter>3 mm.) to house dust mite (D. pteronyssinus) and using normal saline as the negative control.
• Stopped taking all medicine before the study such as antihistamine for at least 3 days, oral steroid and nasal steroid for at least 2 weeks and luekotriene receptor antagonist for at least a week prior to the study, but the patients could take pseudo ephedrine.

Exclusion criteria

• Asthma, Chronic rhino-sinusitis, Hypertension, Cardiovascular diseases
• A smoking habit

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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15 participants in 3 patient groups

Running

Experimental group

Description:

Running on treadmill in moderate intensity for 30 minutes

Treatment:

Other: Running

Cycling

Experimental group

Description:

Cycling on ergometer in moderate intensity for 30 minutes

Treatment:

Other: Cycling

Swimming

Experimental group

Description:

Swimming in moderate in tensity for 30 minutes

Treatment:

Other: Swimming