Acute Eosinophilic Myocarditis International Registry

Niguarda Hospital

Status: Completed

Conditions: Myocarditis

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06447935

NIGUARDA H

Details and patient eligibility

About

Retrospective collection of clinical, histological, imaging data regarding patients with acute histologically-proven eosinophilic myocarditis.

Full description

Eosinophilic myocarditis (EM) is an acute life-threatening inflammatory disease of the heart. We collect clinical, histologic, laboratory, diagnostic and imaging data regarding acute EM with a histological diagnosis and symptoms onset within 30 days from first medical contact from hospitals around the world. The main objective is to investigate and describe clinical presentation, main systemic conditions associated and outcomes of the first series of patients with acute myocarditis and histological evidence of eosinophilic infiltration within myocardium.

Enrollment: 100 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Patients with histological diagnosis gained during an hospitalization within 30 days from symptoms onset.

Trial design

100 participants in 1 patient group

Acute Eosinophilic Myocarditis

Description:

Patients affected by Acute Eosinophilic Myocarditis with the following inclusion criteria: 1. histologically EM proven "borderline" (presence of inflammatory infiltrate) or "active" (presence of inflammatory infiltrate plus myocardial necrosis) myocarditis, according to the Dallas criteria; 2. acute presentation defined by the onset of cardiac symptoms within 30 days before admission.

Treatment:

Other: No intervention