Acute Immunological Effects of Exercise in Cancer Patients (ACTIVE)

Universität Duisburg-Essen

Status and phase: Active, not recruiting; Phase 2

Conditions: Cancer

Treatments: Behavioral: High intensity interval exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT05656651

ACTIVE

Details and patient eligibility

About

The aim of the study is to evaluate and compare immune response to a single exercise intervention in cancer patients and healthy age-maged individuals.

Enrollment: 60 estimated patients

Sex: All

Ages: 15+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adolescents and young adults >14 years of age
• undergoing acute cancer treatment (chemotherapy)
• signed informed consent

Exclusion criteria

• Inability to follow and implement test instructions
• medical contraindication to HIIT on cycle ergometer
• chemotherapeutic treatment 48 h prior
• Hb <8g/dl; platelets < 20,000/ul.

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Cancer patients

Experimental group

Description:

Single exercise intervention following a HIIT protocol, duration \~20 mins

Treatment:

Behavioral: High intensity interval exercise training

Healthy adults

Active Comparator group

Description:

Single exercise intervention following a HIIT protocol, duration \~20 mins

Treatment:

Behavioral: High intensity interval exercise training