Acute Kidney Injury After Cardiac Arrest

Bakirkoy Dr. Sadi Konuk Training and Research Hospital

Status: Completed

Conditions: Acute Kidney Injury

Study type: Observational

Funder types: Other

Identifiers

NCT06544538

2023/250

Details and patient eligibility

About

The development of AKI (Acute Kidney Injury) after cardiac arrest is a common factor associated with mortality. In this study, we aimed to evaluate the factors that increase the risk of developing AKI after cardiac arrest.

For the study, patients were evaluated for the incidence of acute kidney injury (AKI), factors that increase the risk of AKI, and the impact of AKI on mortality. In this process, demographic data, comorbidities, hemodynamic data, laboratory data, clinical symptoms and findings recorded in the electronic decision support system were recorded and analyzed.

Full description

This retrospective study was performed on patients hospitalized in intensive care units after cardiac arrest between 2013 and 2022. Patients who met the inclusion criteria were included in the study. Urea, creatinine values, and whether AKI was diagnosed or not were obtained from the data registry system. Statistical evaluation was performed using univariate binary logistic regression analysis.

Demographic data, location of cardiac arrest (in-hospital, out-of-hospital), and duration of CPR were recorded. In addition, the causes of cardiac arrest, HR/MAP (heart rate/average arterial pressure) ratio, and whether VSP (vasopressor) or INO (inotropic) medication was needed were recorded.

Enrollment: 82 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients with spontaneous circulation after cardiac arrest and admitted to the intensive care unit

Exclusion criteria

• Deaths in the first 48 hours

• Missing data

• End stage CKD or first day hemadsorption

• CPR time <3 min

• Unwitnessed cardiac arrest

• Terminal malignancy

  • 90 years old

• Having a pace marker

• Massive bleeding

• ECMO application

• First day diyabetes insipitus

Trial design

82 participants in 2 patient groups

AKI Group

Description:

AKI 1-3 in the first 48 hours after cardiac arrest according to KDIGO 2012 criteria

Non-AKI Group

Description:

Those who did not develop AKI in the first 48 hours after cardiac arrest according to KDIGO 2012 criteria