Acute Kidney Injury After Craniotomy

Capital Medical University

Status: Completed

Conditions: Acute Kidney Injury; Risk Factor; Epidemiology

Treatments: Other: As a observational study, there is no intervention.

Study type: Observational

Funder types: Other

Identifiers

NCT03789747

Beijing Tiantan Hospital

Details and patient eligibility

About

The aim of this study was to investigate the incidence, risk factors and prognosis of acute kidney injury (AKI) in critically ill patients after craniotomy.

Full description

This was a prospective, single-center, cohort study that included adult patients who were admitted to the ICU of Beijing Tiantan Hospital from January 2017 to December 2018 after craniotomy and had a stay in the ICU for ≥ 24 hours (patients with preoperative AKI were excluded). Data collected included patient demographics (age, gender, underlying diseases, baseline serum creatinine, etc.), primary diagnosis, perioperative information, disease severity scores, as well as the occurrence of hypernatremia and hyperchloremia within 48 hours after ICU admission. For patients with AKI, pre-AKI sepsis and shock, and the recovery of renal function were recorded. All patients were followed until discharge, and information about prognosis was recorded. Multivariate regression analysis was used to identify the risk factors of AKI.

Enrollment: 143 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients underwent craniotomy
• admitted into ICU ward and the ICU length of stay ≥24h

Exclusion criteria

• Age< 18 years;
• Patients with pre-existing acute kidney injury (AKI) and chronic kidney disease undergoing long-term renal replacement therapy (RRT) .