Acute Kidney Injury and Recovery Mode in Pediatric Liver Transplantation

Tianjin First Central Hospital

Status

Completed

Conditions

Postoperative Acute Kidney Injury

Pediatric Liver Transplantation

Treatments

Other: No Intervention: Observational Cohort

Study type

Observational

Funder types

Other

Identifiers

NCT06598228

20240903-1

Details and patient eligibility

About

Acute kidney injury (AKI) is a common complication after pediatric liver transplantation (PLT), and renal impairment after LT has proven to be related with increased graft failure and mortality. The recovery mode of kidney injury after PLT has not been systematically studied. Therefore, in this study the investigators aimed to systematically evaluate prognosis of AKI after PLT, combine the recovery mode of AKI with related risk factors, and establish a relationship between AKI and CKD.

Enrollment

700 patients

Sex

All

Ages

Under 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients who received a liver transplant for the first time.
Patients who were younger than 18 years of age at the time of transplant.

Exclusion criteria

Patients with incomplete clinical data.
Patients with less than 5 years of follow-up.
Patients who have combined multiple solid organ transplants.
Patients with preoperative renal impairment (eGFR<60ml/min/1.73 m2 or prior renal replacement therapy).