Acute Kidney Injury Biomarkers: Diagnosis and Application in Pre-operative Period of Liver Transplantation (AKIB)

University of Sao Paulo

Status: Unknown

Conditions: Acute Kidney Injury

Study type: Observational

Funder types: Other

Identifiers

NCT02095431

10393 (Registry Identifier)

2013/12710-2 (Other Grant/Funding Number)

Details and patient eligibility

About

Acute kidney injury (AKI), is a common complication of patients undergoing liver transplantation. Timing and definition of AKI, usually based on serum creatinine, have been inaccurate and inconsistent.

We hypothesized that the pattern of novel biomakers elevation could be a prognostic tool to provide information on the risk of progression of AKI, the need for RRT and mortality.

Enrollment: 122 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Older than 18 years
• Reception liver transplantation

Exclusion criteria

• CKD stage 4 / 5
• Combined organ transplants
• Patients receiving dialysis before liver transplant operation

Trial design

122 participants in 1 patient group

with AKI and without AKI

Description:

development of AKI by sCr and by novel biomarkers