Acute Kidney Injury in Adult Patients Supported by VA-ECMO (AKI-ECMO)

Groupe Hospitalier Pitie-Salpetriere

Status: Completed

Conditions: Acute Kidney Injury; Cardiogenic Shock

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04082312

AKI-ECMO

Details and patient eligibility

About

Post-cardiotomy cardiogenic shock (PCCS) occurs in 2-6% of patients undergoing cardiac surgery, and 1% of cardiac surgery patients will require mechanical circulatory support using Veno-Arterial ExtraCorporeal Membrane Oxygenation (VA-ECMO). Acute Kidney Injury is a frequent complication in this population and negatively impacts the survival. We aimed to determine whether the timing of ECMO implantation influence the renal prognosis of these patients.

Enrollment: 347 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients admitted in post-operative of cardiac surgery
• Assisted by VA-ECMO

Exclusion criteria

• Chronic hemodialysis
• Death occurring within the first 48 hours of VA-ECMO implantation
• Multiple VA-ECMO during the same hospitalization.

Trial design

347 participants in 3 patient groups

Group 1

Description:

Patients admitted in the surgical intensive care unit in post-operative of cardiac surgery between January 2013 and December 2016 + Assisted by VA-ECMO + with KDIGO stage 3 AKI

Treatment:

Other: No intervention

Group 2

Description:

Patients admitted in the surgical intensive care unit in post-operative of cardiac surgery between January 2013 and December 2016 + Assisted by VA-ECMO + without KDIGO stage 3 AKI and alive at D10

Treatment:

Other: No intervention

Group 3

Description:

Patients admitted in the surgical intensive care unit in post-operative of cardiac surgery between January 2013 and December 2016 + Assisted by VA-ECMO + died before D10 without KDIGO stage 3 AKI

Treatment:

Other: No intervention