Acute Lung Injury After Aortic Valve Surgery

University of Oulu

Status: Unknown

Conditions: Lung Injury

Treatments: Procedure: aortic valve surgery with CPB

Study type: Observational

Funder types: Other

Identifiers

NCT01184313

Mikkola2010

Details and patient eligibility

About

The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery.

Study questions:

• Is there any correlation between the release of pro-inflammatory biomarkers and lung injury degree?
• Is there any correlation between oxyhaemodynamic parameters and lung injury degree?
• Is there any correlation between oxyhaemodynamic parameters and the release of pro-inflammatory biomarkers?
• Are budesonide, erdostein and acetylcystein effective in the prevention of lung injuries?

Enrollment: 100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• elective aortic valve surgery patient
• written consent

Exclusion criteria

• none

Trial design

100 participants in 1 patient group

aortic valve surgery

Treatment:

Procedure: aortic valve surgery with CPB