Acute Pain and Inflammation After Surgery (Knemikro01)

University of Oslo (UIO)

Status and phase: Completed; Phase 4

Conditions: Knee Injuries

Treatments: Drug: Placebo; Drug: 1 Ketorolac intraarticular

Study type: Interventional

Funder types: Other

Identifiers

NCT00774540

S-04342

Knemikro01

Details and patient eligibility

About

The purpose of this study is

1. to observe acute pain after surgery and measure the natural course of inflammatory mediators
2. study pain relieving effects and local anti-inflammatory effects of systemically administered ketorolac

Full description

Randomizized controlled trial

Enrollment: 40 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Day case surgical patients above 18 years old
• Non pregnant

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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40 participants in 2 patient groups, including a placebo group

1

Experimental group

Description:

Ketorolac

Treatment:

Drug: 1 Ketorolac intraarticular

2

Placebo Comparator group

Description:

saline

Treatment:

Drug: Placebo