Acute Pain Memory Among Former Burned: Exploration of fMRI. (EXPLO-DMA)

Centre Hospitalier Universitaire de Saint Etienne

Status: Terminated

Conditions: Neuronal Activity; Magnetic Resonance Imaging

Treatments: Other: fMRI

Study type: Interventional

Funder types: Other

Identifiers

NCT03224975

ID-RCB (Other Identifier)

1708030

Details and patient eligibility

About

Pain is complex phenomenon misunderstood in spite of medical progress and neurosciences. That's why the relief of chronic pain is only partial for a lot of infection as arthrosis, chronic back pain, headaches or neuropathic pain. Certain situations bring to relive pain sensation. Investigators were interested to former burned. They wonder about somatic memory and unconscious of acute.

Full description

It is a comparative and monocentric study. There are two groups. On the one hand, there is the former burned and, on the other hand, healthy volunteers. While they thought to painful memory or not, functional Magnetic Resonance Imaging (fMRI) will be performed. Then, investigators compare two functional Magnetic Resonance Imaging (fMRI).

Main objective of this study is link up between brain activity by functional Magnetic Resonance Imaging (fMRI) and acute pain memory.

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

For control group:

• Affiliated or entitled to a social security
• Have signed consent before their participation in the study
• Adult women and men french and is right handed
• Vision and hearing normal or corrected

For former burned:

• Affiliated or entitled to a social security
• Have signed consent before their participation in the study
• Adult women and men french and is right handed
• Vision and hearing normal or corrected
• Localized burn at the hand or feet onset between 12 and 24 years
• Not sequelae painful at the inclusion
• Scope and depth of the burn according to classifications CIM 10

Exclusion criteria

For control group:

• Any contraindications to pass an fMRI test
• Neuropathic pains and psychiatric disorders
• Medical history of head injuries
• Burn presence

For former burned:

• Any contraindications to pass an fMRI test
• Neuropathic pains and psychiatric disorders
• Medical history of head injuries

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

patients

Experimental group

Description:

Patient who was burned will have fMRI.

Treatment:

Other: fMRI

control group

Active Comparator group

Description:

Healthy volunteers (control group) will have fMRI.

Treatment:

Other: fMRI