Acute Sodium Bicarbonate Supplementation in Athletes

Poznan University of Physical Education

Status and phase: Active, not recruiting; Phase 3

Conditions: Supplementation; Sport

Treatments: Dietary Supplement: Sodium bicarbonate supplementation; Dietary Supplement: Placebo treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT03810404

ULS00006

Details and patient eligibility

About

The purpose of this study is to verify the effect of acute sodium bicarbonate (SB) and placebo (PLA) supplementation on buffering potential kinetics, physical capacity, discipline-specific performance as well as concentration of diagnostically significant blood biochemical indices in athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Full description

Effective muscle work is conditioned by maintaining the proper range of muscles pH, regulated by buffering systems, in which the main role is played by bicarbonates (HCO3-). For this reason, sodium bicarbonate (SB) is often proposed as an ergogenic agent, especially during high-intensity efforts. Until now the major limitation to SB supplementation has been the gastrointestinal (GI) side effects. There is also a lack of data of the individual SB-induced changes of buffering potential kinetics and its actual connection with physical capacity and discipline-specific performance. Therefore, this study aims to examine the effect of acute, different-dose SB ingestion on buffering potential kinetics, physical capacity, discipline-specific performance as well as changes of diagnostically significant blood biochemical indices concentration in athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• written consent to participate,
• a current medical clearance to practice sports,
• training experience: at least 2 years,
• minimum of 4 workout sessions (in the discipline covered by the study) a week.

Exclusion criteria

• current injury,
• any health-related contraindication,
• declared general feeling of being unwell,
• unwilling to follow the study protocol.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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50 participants in 2 patient groups, including a placebo group

Sodium bicarbonate supplementation

Experimental group

Description:

Group taking oral SB supplementation in a different-dose regimen.

Treatment:

Dietary Supplement: Sodium bicarbonate supplementation

Placebo treatment

Placebo Comparator group

Description:

Group taking oral supplementation with placebo (NaCl).

Treatment:

Dietary Supplement: Placebo treatment