Adapted Physical Activity Education in Patients With Neurocognitive Disorder (EduAPA)

Centre Hospitalier Universitaire de Nice

Status: Enrolling

Conditions: Neurocognitive Disorders

Treatments: Other: APA; Other: PAE

Study type: Interventional

Funder types: Other

Identifiers

NCT05866822

21-AOI-10

Details and patient eligibility

About

This study aims to compare the effect of a program of Adapted Physical Activity (APA) versus the same program combined with a physical activity education program (PAE). Patients suffering from neurocognitive disorders (mild or early major) will be randomized into one of the two conditions. 3 complete evaluations will be done (inclusion M0, after 3 month of intervention M3, 3 months after the end of the intervention M6). The team except that APA+PEA will be more effectiv than the APA solely, on the following criteria : level of physical activity, cogntive function and quality of life.

Enrollment: 34 estimated patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• mild neurocognitive disorder or early major neurocognitive disorder

Exclusion criteria

• Medical pathology involving the vital prognosis in the short term
• Major neurocognitive disorder at moderate stage and beyond (DSM 5) and/or MMSE < 20
• Unbalanced depressive syndrom
• Contraindication to the practice of the exercises proposed during the study;
• Major hearing or visual impairment;
• Sufficiently active with regard to the daily recommendations described by the WHO

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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34 participants in 2 patient groups

APA (adapted physical activity)

Active Comparator group

Description:

24 APA sessions will take place, there will be 2 sessions a week for 12 weeks which will include global exercises for the upper and lower limb. One session will be 1 hour long and supervised by professionals. It will be divided in 4 cycles which will be differentiated by the intensity of its components: aerobic, strength, speed, balance, coordination and flexibility. The intensity of the sessions will be measured by RPE and heart rate monitor,

Treatment:

Other: APA

APA (adapted physical activity) + physical activity education (PAE)

Experimental group

Description:

24 APA sessions will take place, there will be 2 sessions a week for 12 weeks which will include global exercises for the upper and lower limb. One session will be 1 hour long and supervised by professionals. It will be divided in 4 cycles which will be differentiated by the intensity of its components: aerobic, strength, speed, balance, coordination and flexibility. The intensity of the sessions will be measured by RPE and heart rate monitor, + 8 individuals sessions of PAE (one per week, half an hour long) that will consist of advising and setting weekly goals related to improving PA level and sedentary behavior

Treatment:

Other: PAE

Other: APA