Adapted Physical Activity for Breast Cancer HER2 Positive Patient (APACAN2)

Centre Jean Perrin

Status: Terminated

Conditions: HER2 Positive Breast Cancer

Treatments: Other: Home-based Adapted Physical Activity

Study type: Interventional

Funder types: Other

Identifiers

NCT02963363

2016-A01344-47

Details and patient eligibility

About

The purpose of this study is to assess the feasibility of a home-based adapted physical activity during neoadjuvant chemotherapy for HER2+ breast cancer.

Full description

After the assessment of their physical fitness, a home-based adapted physical activity program composed by aerobic and muscle strengthening exercises will be delivered to each patient. The aim of the intervention is to reach international recommendation in a progressive way during neoadjuvant chemotherapy.

Enrollment: 36 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women > 18 years old
• Patient with HER2 (Human Epidermal growth factor Receptor 2) positive breast cancer histologically proven, eligible for neoadjuvant chemotherapy and targeted therapy against HER-2
• Affiliation to the French social security scheme
• Patient who signed the participation consent before entering the trial
• Medical fitness certificate for sport

Exclusion criteria

• Diagnosis of a second malignancy in the past 5 years, with the exception of a basal cell skin cancer
• Metastatic cancer
• Karnofsky index ≤ 90%
• Men
• Pregnant women
• Significant psychiatric or neurological abnormality
• Patient deprived of liberty by a court or administrative
• Contraindication for physical activity
• Patient unable to complete questionnaires (language barrier)
• Participation in a clinical trial with the same objective

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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36 participants in 1 patient group

Interventional

Experimental group

Description:

Home-Based Adapted Physical Activity intervention during neoadjuvant chemotherapy : 150 minutes per week of aerobic and muscle strengthening exercises during 18 weeks

Treatment:

Other: Home-based Adapted Physical Activity