Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes

Taichung Veterans General Hospital

Status: Unknown

Conditions: Impaired Glucose Tolerance; Diabetes Mellitus

Treatments: Drug: Acarbose

Study type: Interventional

Funder types: Other

Identifiers

NCT00417950

950801/C06138

Details and patient eligibility

About

To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes.

Sex: All

Ages: 25 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with mild diabetes without prior medications or impaired glucose tolerance

Exclusion criteria

• Pregnancy
• Recent major cardiac, renal and hepatic disease
• Intolerance to alcohol
• Allergy to acarbose treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)