Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Multicenter Cohort Study) III

Nanjing Medical University

Status: Completed

Conditions: Aortic Dissection

Treatments: Biological: inflammatory response

Study type: Observational

Funder types: Other

Identifiers

NCT04918108

5A Plan

Details and patient eligibility

About

Anatomopathological classifications have been well identified in aortic dissection with important therapeutic implications. The authors evaluated the inflammatory response in patients with aortic dissection (AD) and assessed the presence of distinct inflammatory subphenotypes within this disease.

Enrollment: 2,000 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• acute type Aortic dissection;

Exclusion criteria

• Iatrogenic aortic dissection OR traumatic aortic dissection
• Patients with hematological diseases, infectious diseases, malignant tumors, immune system diseases, or severe liver diseases.
• Preoperative use of mechanical ventilation, blood transfusion, renal replacement therapy, extracorporeal membrane oxygenation, or intra-aortic balloon pump during the current admission.

Trial design

2,000 participants in 1 patient group

inflammatory subphenotype

Treatment:

Biological: inflammatory response