Additive Effects of Alternative Nostril Breathing with Pharmacological Management on Dyspnea and Control Pause in Patients with Bronchial Asthma

Foundation University Islamabad

Status: Enrolling

Conditions: Bronchial Asthma

Treatments: Drug: Pharmacological therapy; Other: Alternative nostril breathing

Study type: Interventional

Funder types: Other

Identifiers

NCT06609941

FUI/CTR/2024/25

Details and patient eligibility

About

Bronchial asthma is a widespread chronic condition charactrized by inflammation and narrowing of airways, leading to repeateted episodes of breathlessness, wheezing and labored breathing.Breathing exercises help to manage hyperventilation often seen in asthmatic patients. To handle respiratory complications asthmatics are advised to practise nasal breathing techniques in conjunction with their prescribed medications.

Full description

Bronchial asthma is a very common chronic disease marked by inflammation and constriction of airways, resulting in recurrent episodes of breathlessness, wheezing and decrease work of breathing. Breathing exercises help to manage hyperventilation associated with asthma. In order to manage respiratory conditions asthmatic patients are encouraged for nasal breathing techniques along with pharmacological management. Hence the objective of the study is to compare the effects of alternative nostril breathing along with pharmacological management versus pharmacological management alone on dyspnea, control pause, asthma control and peak expiratory flow rate in patients with bronchial asthma.

Enrollment: 32 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults: aged (18-45 years)
• Gender: Both males and females
• Grade1- Grade 4 on Modified MRC dyspnea scale
• Asthma severity classes (intermediate, mild persistent and moderate persistent asthma) acc. to NAEPP national asthma education and prevention program guidlin

Exclusion criteria

• Patients having acute exacerbation of COPD or status asthmaticus
• Patients diagnosed with acute infections
• Patients unable to follow command/ instructions
• Asthma patients with >40 sec control pause duration
• Patients who fall in red zone of asthma action plan (PEFR < 50%)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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32 participants in 2 patient groups

Nostril Breathing along with pharmacological therapy Group

Experimental group

Description:

Patients in this group will receive alternative nostril breathing along with pharmacological management. Total 4 weeks protocol. Two sessions per week will be supervised by physiotherapist and 5 days at home. A home diary will be provided in order to ensure and follow-up that participants are performing breathing exercise at home.

Treatment:

Other: Alternative nostril breathing

Drug: Pharmacological therapy

Pharmacological therapy Group

Active Comparator group

Description:

Patients will receive medication as prescribed by pulmonologist through stepwise approach according to symptoms and severity. Total 4 weeks protocol. Before and after 4 weeks pre and post interventional values will be taken.

Treatment:

Drug: Pharmacological therapy