Adductor Canal Block and Arthroscopic Knee Surgery, High Pain Responders

Glostrup University Hospital, Copenhagen

Status and phase: Completed; Phase 4

Conditions: Arthroscopic Knee Surgery

Treatments: Procedure: Intervention group, block no. 1 - Ropivacain; Procedure: Control group: 1. block - saline

Study type: Interventional

Funder types: Other

Identifiers

NCT02001662

H-3-2013-039 (Other Identifier)

2013-000663-83 (EudraCT Number)

SM3-ME-13

Details and patient eligibility

About

The investigators want to explore the analgesic effect of Adductor Canal Blockade (a peripheral nerve block) in high pain responding patients after arthroscopic knee surgery. The investigators hypothesize that the nerve block will have an abrupt analgesic effect.

Enrollment: 50 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Arthroscopic knee surgery, if reconstruction of Anterior Cruciate Ligament only hamstring graft 18-80 years of age BMI 18-40 ASA I-III written Consent

Exclusion criteria

Unable to communicate in danish, allergic reactions toward any study medication pregnancy alcohol/drug abuse daily opioid consumption scin infection (injection site)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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50 participants in 2 patient groups

Intervention group, block no. 1 - Ropivacain

Experimental group

Description:

Adductor-Canal-Block no.1: 30mL ropivacaine (7.5 mg/ml) when postoperative VAS-score is \> 40mm (on a 0-100 mm VAS-scale) during a 45 degree active flexion of the knee. Adductor-Canal-Block no.2: after 45 min (t45) - 30mL isotonic saline.

Treatment:

Procedure: Intervention group, block no. 1 - Ropivacain

Control group, block no. 1 - saline

Sham Comparator group

Description:

Adductor-Canal-Block no.1: 30mL isotonic saline when postoperative VAS-score is above 40mm (on a 0-100 mm VAS-scale) during a 45 degree active flexion of the knee. Adductor-Canal-Block no.2: after 45 min (t45) - 30mL ropivacaine (7.5 mg/ml)

Treatment:

Procedure: Control group: 1. block - saline