Adductor Canal Block and Effect of 10 Versus 30 ml Ropivacaine on Muscle Strength: a Randomized Study in Healthy Volunteers

Rigshospitalet

Status and phase: Completed; Phase 4

Conditions: Healthy Volunteers; Muscle Strength

Treatments: Procedure: Adductor canal block with ropivacaine 0.1%

Study type: Interventional

Funder types: Other

Identifiers

NCT01981746

SM2-PJ-13

Details and patient eligibility

About

To investigate whether reducing the volume (30 versus 10 ml) ropivacaine injected can reduce the number of subjects with impaired muscle strength following adductor canal block. We hypothesized that adductor canal block with 10 ml 0.1% ropivacaine preserves quadriceps strength compared with an adductor canal block with 30 ml.

Enrollment: 26 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-30 years
• Men
• ASA 1
• Body Mass Index 18-25

Exclusion criteria

• Allergy to study medication
• Earlier trauma or surgery to the lower limb
• Diabetes Mellitus

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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26 participants in 2 patient groups

30 ml

Experimental group

Description:

30 ml ropivacaine 0.1%, single bolus

Treatment:

Procedure: Adductor canal block with ropivacaine 0.1%

10 ml

Experimental group

Description:

10 ml 0.1% ropivacaine, single bolus

Treatment:

Procedure: Adductor canal block with ropivacaine 0.1%