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Adductor Canal Block for Medial Compartment Knee Arthroplasty

Wake Forest University (WFU) logo

Wake Forest University (WFU)

Status and phase

Completed
Phase 4

Conditions

Postoperative Analgesia
Medial Unicompartmental Knee Arthroplasty

Treatments

Drug: Lumbar plexus block
Drug: Adductor canal block

Study type

Interventional

Funder types

Other

Identifiers

NCT01818531
IRB00023002

Details and patient eligibility

About

This study will evaluate the affects of a single injection ultrasound-guided adductor canal block for patients undergoing robotic-assisted (MAKOplasty) medial UKA (unicompartmental knee arthroplasty). Specifically, this study will compare the adequacy of postoperative analgesia provided by the adductor canal block with that provided by single injection lumbar plexus blockade. The working hypothesis is that the analgesia provided by the adductor canal block will be equivalent to the analgesia provided by the lumbar plexus block. The primary outcome will be a comparison of verbal numerical pain scores at rest and with movement over the first 24 hours following nerve blockade.

Enrollment

150 patients

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients aged 18-85
  • Undergoing unilateral robotic-assisted (MAKOplasty) medial compartment knee arthroplasty at Wake Forest University Baptist Medical Center.
  • Must give written informed consent for anesthesia including subarachnoid blockade and peripheral nerve blockade of both the lumbar plexus and adductor canal.
  • Must consent to the performance of a sham block at the site to which they are not randomized.
  • Must also be reliable to give accurate verbal pain scores postoperatively.

Exclusion criteria

  • Contraindication to adductor canal blockade or lumbar plexus blockade (including significant coagulation abnormalities)
  • History of opioid addiction or current chronic pain therapy for pain other than at the surgical site that is being treated with high-dose opioids (extended release opioids or > 40mg oxycodone equivalents per day)
  • Allergy to study medications
  • Failure to adequately place either the adductor canal or lumbar plexus blocks.
  • Patients who decline or have a contraindication to subarachnoid blockade will also be excluded from the study.
  • Pregnancy.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

150 participants in 2 patient groups

Adductor canal block
Experimental group
Description:
Patients in this arm will receive an adductor canal block prior to undergoing a medial compartment knee arthroplasty.
Treatment:
Drug: Adductor canal block
Lumbar plexus block
Active Comparator group
Description:
Patients in this arm will receive a lumbar plexus block prior to undergoing a medial compartment knee arthroplasty.
Treatment:
Drug: Lumbar plexus block

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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