Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament Repair

Pontificia Universidad Catolica de Chile

Status and phase: Withdrawn; Phase 1

Conditions: Surgery; Stress, Physiological; Anesthesia

Treatments: Device: Morphine Patient Controlled Analgesia; Procedure: Adductor Canal Block

Study type: Interventional

Funder types: Other

Identifiers

NCT04797546

16-128

Details and patient eligibility

About

To evaluate the surgical stress response in anterior cruciate ligament repair with an adductor canal block versus patient controlled endovenous analgesia.

Full description

Preoperative, 2 hours and 24 hours stress biomarkers will be evaluated in two groups of patients, continous adductor canal block and morphine patient controlled endovenous analgesia.

Sex: Male

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male,
• 18-65 years,
• traumatic Anterior Cruciate Ligament tear, scheduled for elective arthroscopic repair with Semitendinous-Gracillis technique at first time in the morning, with full articular range,
• no other traumatologic lesions.

Exclusion criteria

• denied consent to participate,
• chronic steroids user,
• diabetes type 1 or 2,
• insulin resistance,
• concurrent infectious disease,
• cognitive failure, coagulopathy,
• allergy to study drugs,
• surgery scheduled in the afternoon

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

Adductor Canal Block

Experimental group

Description:

With mild sedation, a continous bupivacaine 0.1% infusion catheter is placed in the adductor canal. Afterwards, patients are placed under General Anesthesia, and surgery starts. Preoperative, 2 hours and 24 hours stress biomarkers and analgesic quality will be measured.

Treatment:

Procedure: Adductor Canal Block

Patient Controlled Morphine Analgesia

Active Comparator group

Description:

Patients are placed under General Anesthesia, and after surgery, a Morphine patient controlled analgesia delivery system is installed. Preoperative, 2 hours and 24 hours stress biomarkers and analgesic quality will be measured.

Treatment:

Device: Morphine Patient Controlled Analgesia