Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption

Pia Jaeger

Status and phase

Completed

Phase 4

Conditions

Postoperative Pain

Treatments

Drug: ropivacaine 0.2%

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT02539628

SM3-PJ-14

2014-005642-22 (EudraCT Number)

Details and patient eligibility

About

The investigators believe sufficient spread to all nerves within the adductor canal-and thereby sufficient analgesia-can only be obtained by bolus injections and not by continuous infusions via a catheter. The aim of the study is to investigate whether an adductor canal block performed as repeated intermittent boluses provides superior pain relief to continuous infusion. The investigators hypothesize that adductor canal block performed as intermittent boluses via a catheter will reduce morphine consumption and pain as well as enhance ambulation and muscle strength compared with continuous infusion.

Enrollment

110 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients scheduled for total knee arthroplasty in spinal anesthesia
Patients who gave their written informed consent to participating in the study after having fully understood the contents of the protocol and restrictions
American society of anesthesiologists 1-3
Ability to perform a timed up and go test preoperatively

Exclusion criteria

Patients who cannot cooperate
Patients who cannot understand or speak Danish.
Patients with allergy to the medicines used in the study
Patients with a daily intake of strong opioids (morphine, oxycodone, ketobemidone, methadone, fentanyl) during the last 4 weeks
Patients suffering from alcohol and/or drug abuse - based on the investigator's assessment
Rheumatoid arthritis
BMI > 40
Neuromuscular pathology in the lower limbs
Pregnancy