Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers

Rigshospitalet

Status and phase: Completed; Phase 4

Conditions: Healthy Volunteers; Muscle Strength

Treatments: Procedure: The femoral nerve block; Procedure: Adductor-Canal-Blockade; Procedure: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01449097

SM2-PJ-11

Details and patient eligibility

About

The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the femoral nerve block versus placebo on muscle strength in healthy volunteers. The investigators hypothesize that the Adductor-Canal-Blockade results in a lesser reduction of the quadriceps muscle strength compared to the femoral nerve block.

Enrollment: 12 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• written informed consent
• ASA 1
• BMI > 18 og < 25

Exclusion criteria

• Can not cooperate to the exam
• Do not speak or understand Danish
• Drug allergy
• Alcohol or drug abuse
• Daily consumption of analgetics on prescription
• Any drug intake within the last 48 hours
• Neuromuscular defects in the femoral nere, the obturator nerve or the muscles of the thigh.
• Previous surgery or trauma to the lower limb
• Diabetes Mellitus
• Intake of steroids, except steroids for inhalation
• Physical exercise within the last 24 hours prior to Day 1 and 2 of the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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12 participants in 3 patient groups, including a placebo group

Adductor-Canal-Blockade

Experimental group

Treatment:

Procedure: Adductor-Canal-Blockade

The femoral nerve block

Active Comparator group

Treatment:

Procedure: The femoral nerve block

Placebo

Placebo Comparator group

Treatment:

Procedure: Placebo