Adherence, Efficacy and Safety of an Insulin Protocol in the Critically Ill: A Prospective Observational Study

Ghent University Hospital (UZ)

Status and phase: Completed; Phase 2

Conditions: Critically Ill Patients

Treatments: Drug: to implement an insulin protocol with target blood glucose levels between 81-110 mg/dL.

Study type: Interventional

Funder types: Other

Identifiers

NCT00288743

2002/087

Details and patient eligibility

About

There is a growing body of evidence in the literature regarding the adverse effects of hyperglycemia in critically ill patients. To target and maintain better blood glucose regulation we implemented an insulin protocol with target blood glucose levels between 81-110 mg/dL.

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Surgical or medical critically ill patients
• An expected ICU-stay of more than 72 hours
• Age > 16 years
• Need for insulin therapy
• Patients must have an arterial line

Exclusion criteria

• Patients who did not respond to the inclusion criteria
• Patients with diabetic ketoacidosis
• Cardiac surgical patients
• Patients transferred from other hospitals
• Other study enrollment

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)