Adherence to Mesalamine Profile for Patients With Inflammatory Bowel Disease
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Details and patient eligibility
About
Hypothesis:
Mesalamine is commonly used to induce and maintain remission in patients with Inflammatory Bowel Disease (IBD). Behavioral and psycho-social barriers to mesalamine adherence exist in patients with IBD. These factors can be identified using qualitative testing in order to develop a validated instrument to measure the "adherence profile" of an individual patient, and design appropriate behavioral interventions to reduce non-adherence.
Objectives:
To test a novel interview instrument that determines the medication adherence profile of patients with IBD prescribed mesalamine by correlating with objective measures of adherence
Full description
Specific Aims:
To test a novel interview instrument to classify patients into "adherence profiles" To validate this instrument with quantitative scores of mesalamine adherence and objective testing.
Study Design Rationale:
Qualitative research design and prospective validation
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Adult patient (age >18)
- Diagnosis of IBD (confirmed by endoscopy and histology) > 3 months
- In clinical remission (based on Simple Colitis Activity Index score <2.5)
- On mesalamine compound for maintenance of remission
- Stable mesalamine dose for 1 month
Exclusion criteria
- Not receiving primary GI care at BIDMC
Trial design
106 participants in 1 patient group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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