Adiponectin and Ethnic Differences in Insulin Resistance

University of Colorado Denver (CU Denver)

Status: Completed

Conditions: Insulin Resistance; Type 2 Diabetes

Treatments: Other: none- observational study

Study type: Observational

Funder types: Other

Identifiers

NCT01831102

10-1260

Details and patient eligibility

About

The purpose of this protocol is to measure and compare levels of the circulating protein adiponectin and adiponectin's association with insulin sensitivity in Mexican Americans and non-Latino white subjects. The investigators also aimed to examine associations between nutritional factors and adiponectin levels.

Enrollment: 43 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-60 years of age
• BMI 20.0-34.9 m/kg2
• Mexican American with at least 3 grandparents born in Mexico or white with no grandparents of Latino descent.

Exclusion criteria

• pregnancy
• breastfeeding
• diabetes mellitus
• blood pressure > 160/100 mmHg
• creatinine > 1.5 mg/dl or glomerular filtration rate (GFR) < 60
• liver function tests > 3x upper limit of normal (ULN)
• h/o heart failure
• h/o eating disorder

Trial design

43 participants in 2 patient groups

non-Latino white

Description:

no Latino ancestry, Caucasian

Treatment:

Other: none- observational study

Mexican American

Description:

Mexican American ancestry

Treatment:

Other: none- observational study