Adiponectin and Insulin Resistance in Diabetic Nephropathy

Health Science Center of Xi'an Jiaotong University

Status: Completed

Conditions: Diabetic Nephropathy

Treatments: Drug: Losartan

Study type: Interventional

Funder types: Other

Identifiers

NCT00774904

ADPN

Details and patient eligibility

About

Plasma adiponectin concentration is inversely associated with renal function. There is little literature on adiponectin levels and regulation by antihypertensive medication with an angiotensin II-receptor blocker (ARB), especially in subjects with type 2 diabetes in different stage of chronic kidney disease (CKD).

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 2 diabetic nephropathy
• CKD at stage 1~4

Exclusion criteria

• Type 1 diabetes or nondiabetic renal disease
• An elevated plasma K level.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)