Adipose Inflammation and Diabetes (FAB)

Göteborg University

Status: Enrolling

Conditions: Obese

Study type: Observational

Funder types: Other

Identifiers

NCT04255264

2019-04046

Details and patient eligibility

About

The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.

Enrollment: 18 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI 30-40 kg/m2
• Ptos (i.e. excess skin) > 3 cm
• Patient underwent gastric bypass surgery >2 years ago
• Patient has had a stable weight ≥6 months at the time of operation
• Patient does not smoke (min 6 weeks prior to surgery)

Exclusion criteria

• Patients who do not understand spoken and written Swedish
• American Society of Anesthesiologists (ASA) classification ≥ 3
• Neurological, orthopedic or rheumatologic injury or illness affecting physical ability
• Preoperatively known hernia requiring surgical operation
• Severe mental illness

Trial design

18 participants in 1 patient group

Study patients

Description:

Obese subjects scheduled to undergo abdominoplasty surgery are included. These are later classified according to metabolic status.