Adjunctive Local Sodium Hypochlorite Gel in Non Surgical Periodontal Debridement

University of Messina

Status: Completed

Conditions: Periodontal Diseases

Treatments: Drug: Sodium hypochlorite gel application

Study type: Interventional

Funder types: Other

Identifiers

NCT04399187

16-18

Details and patient eligibility

About

The aim of this study was to assess the efficacy of minimally invasive nonsurgical debridement (MINSD) of periodontal pockets with or without local amino acid buffered sodium hypochlorite (NaOCl) gel application after 6 months follow-up.

Full description

Forty periodontal compromised patients were randomly allocated in two groups. Periodontal pockets > 5 mm in patients of test group were treated by MINSD and NaOCl gel application, meanwhile in patients of control group MINSD alone was performed. Full-mouth plaque score (FMPS) , Full-mouth bleeding score (FMBS), probing depth (PD), clinical attachment level (CAL) and gingival recession (GR) were assessed at baseline and after 6 months follow-up.

Enrollment: 40 patients

Sex: All

Ages: 32 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients diagnosed with periodontitis;
• Age > 18 years old;
• Patients with at least 10 teeth for arch;
• Presence at least of two teeth with PD > 5 mm for quadrant;
• Single-rooted and multi-rooted teeth;

Exclusion criteria

• Patients with systemic diseases;
• Pregnant or lactating;
• Tobacco smokers (> 10 cigarettes/day);
• Previous periodontal treatment in the last 2 years;
• Prolonged antibiotic treatment or anti-inflammatory treatment within 6 months prior to periodontal therapy;
• Furcation involvement;
• Acute periodontal or endodontic abscess;
• Third molars

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

scaling and root planing, Sodium hypochlorite gel application

Experimental group

Description:

Periodontal pockets \> 5 mm in patients of test group were treated by scaling and root planing and Sodium hypochlorite gel application

Treatment:

Drug: Sodium hypochlorite gel application

scaling and root planing alone

Placebo Comparator group

Description:

scaling and root planing alone was performed

Treatment:

Drug: Sodium hypochlorite gel application