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Admission HbA1C in Aneurysmal Subarachnoid Hemorrhage

H

Heinrich-Heine University, Duesseldorf

Status

Completed

Conditions

Hyperglycemia
Aneurysmal Subarachnoid Hemorrhage

Study type

Observational

Funder types

Other

Identifiers

NCT02081820
UKD-NCH-2014-001

Details and patient eligibility

About

In patients suffering from aneurysmal subarachnoid hemorrhage (aSAH), hyperglycemia is considered an adverse prognostic factor. Glycated hemoglobin (or HbA1c) can be measured to estimate the average plasma glucose concentration over prolonged periods of time, thus determination of glycated hemoglobin at admission after aSAH serves as an approximation of blood glucose levels in the weeks preceding aneurysm rupture. In this patient registry admission HbA1c, clinical course and neurological outcome after 6 month are recorded, to determine whether elevated blood glucose levels prior to aneurysm rupture influence the clinical course and patient outcome after aSAH.

Full description

In patients suffering from aneurysmal subarachnoid hemorrhage (aSAH), hyperglycemia is considered an adverse prognostic factor. Glycated hemoglobin (or HbA1c) can be measured to estimate the average plasma glucose concentration over prolonged periods of time, thus determination of glycated hemoglobin at admission after aSAH serves as an approximation of blood glucose levels in the weeks preceding aneurysm rupture.

In this patient registry admission HbA1c within 72 hours after confirmed aneurysmal subarachnoid hemorrhage in patients aged over 18 years is determined and correlated with clinical course and neurological outcome after 6 month as determined by modified Rankin score. Additionally, patients are monitored for incidence of delayed cerebral ischemia (DCI) and the incidence of new infarction on the discharge ct scan attributable to DCI. General treatment of cerebral aneurysm and subarachnoid hemorrhage in all patients follows international guidelines.

Enrollment

89 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • confirmed aneurysmal subarachnoid hemorrhage
  • admission within 72hours after hemorrhage
  • Age >18 years

Exclusion criteria

  • non-aneurysmal SAH
  • admission >72hours after hemorrhage
  • Age <18 years

Trial design

89 participants in 1 patient group

aneurysmal subarachnoid hemorrhage
Description:
observational, no intervention

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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