Advanced Radiotherapy (ART) in Gynecological Cancer Patients (GYN-ART)

San Donato Group (GSD)

Status: Enrolling

Conditions: Radiotherapy Side Effect; Progression, Clinical; Progression, Disease; Survivorship; Radiotherapy; Complications; Gynecologic Cancer

Treatments: Radiation: Image Guided Radiotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT06306170

GYN-ART

Details and patient eligibility

About

This is an observational mono-institutional study. Patients with gynecologic tumors treated with advanced radiotherapy- Image Guided Radiotherapy (IGRT), Intensity Modulated Radiotherapy (IMRT), Stereotactic Body Radiotherapy (SBRT)- will be included and toxicity and outcomes analyzed.

Full description

The patients with gynecological cancer treated with Advanced Radiotherapy (ART)- Image Guided Radiotherapy (IGRT), Intensity Modulated Radiotherapy (IMRT), Stereotactic Body Radiotherapy (SBRT)- at the Department of Radiotherapy of "IRCCS San Raffaele Scientific Institute" (IRCCSSRaffaele) from January 2005 to January 2024 will be identified and their clinical and dosimetric data retrieved and analyzed.

The study objectives are the analysis of acute and late toxicity, and clinical outcomes, such as local, regional and distant control,disease free survival, cancer-specific survival, and overall survival. Secondary objective is the identification of prognostic factors for toxicity, disease progression, survival, including radiomic characteristics.

Enrollment: 1,000 estimated patients

Sex: Female

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• gynecologic cancer patients
• >18 years old
• treated with advanced radiotherapy techniques (IGRT, IMRT, SBRT)

Exclusion criteria

• other tumors
• > 90 years old

Trial design

1,000 participants in 1 patient group

Gynecologic cancer patients

Description:

Gynecologic cancer patients treated with IGRT, IMRT, SBRT (advanced radiotherapy-ART)

Treatment:

Radiation: Image Guided Radiotherapy