Aerobic and Strength Training With Caloric Restriction on Insulin Resistance in Obese Premenopausal Women

Cairo University (CU)

Status: Completed

Conditions: Insulin Resistance Syndrome

Treatments: Other: Resistance exercise; Dietary Supplement: diet restriction; Other: Aerobic exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03716336

CairoU90

Details and patient eligibility

About

A total of 42 premenopausal women diagnosed clinically as having insulin resistance. Their ages ranged from 35 to 45 years old; their body mass index was >30 kg/m2 and They were obese women complained of insulin resistance and non diabetic or cardiovascular disease, were randomly assigned to group A participated in aerobic & resistive exercise program, and group B participated in aerobic exercise and followed prescribed diet restriction program. Both of the groups (A&B) followed the treatment program 3 times per weeks for 8 weeks. Assessment of the fasting glucose, fasting insulin, and HOMA test of insulin resistance were measured for all subjects in both groups (A and B) was carried out before and after the end of the treatment program

Full description

Forty two obese premenopausal women diagnosed as having insulin resistance were participated in this study. They were selected randomly from the out Patient Clinic of Obstetrics at Kasr El Ainy University Hospital, Faculty of Medicine, Cairo University. Their age ranged from 35 - 45years, their body mass (BMI) were>30kg/m2. Exclusion criteria of the study were as follows: Patients having diabetic or cardiovascular disease, Patients with life threatening disorders as renal failure and myocardial infarction, Patients with active malignancy and patients with severe hemorrhage, hyperthyroidism, acute viral diseases and mental disorders. Participants were assigned randomly used sealed envelope into two groups (A&B) equally in number. Group (A): (Combined resistive and aerobic exercise group) consisted of 20 women were participated in aerobic & resistive exercise program plus diet restriction, 3 times per weeks for 8 weeks. Group (B): consisted of 20 women were participated in aerobic exercise plus diet restriction 3 times per weeks for 8 weeks.

Enrollment: 40 patients

Sex: Female

Ages: 35 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Their age ranged from 35 - 45years.
• their body mass (BMI) were>30kg/m2.

Exclusion criteria

• Patients having diabetic or cardiovascular disease.
• Patients with life threatening disorders as renal failure and myocardial infarction
• Patients with active malignancy.
• patients with severe hemorrhage
• hyperthyroidism.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

aerobic exercise

Other group

Description:

walking on treadmill

Treatment:

Other: Aerobic exercise

Other: Resistance exercise

Dietary Supplement: diet restriction

resistive exercise

Other group

Description:

Resistance exercise were performed for all participants in group (A) included 9 exercise for big muscles of upper limbs

Treatment:

Other: Aerobic exercise

Other: Resistance exercise

Dietary Supplement: diet restriction