Aerobic Capacity and Physical Fitness Level of Adolescents With PCOS

Hacettepe University

Status: Completed

Conditions: Polycystic Ovary Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT05246306

GO 21/947

Details and patient eligibility

About

Polycystic Ovary Syndrome (PCOS) is associated with hyperandrogenism, hyperinsulinemia and insulin resistance starting in the perimenarchal period. Insulin resistance also increases the risk of developing glucose intolerance, type 2 diabetes, hypertension, dyslipidemia and cardiovascular disorders. Studies on adult women with PCOS show that their aerobic capacity is affected. Therefore, in this study; it was aimed to compare the physical and cardiovascular fitness levels of adolescent PCOS patients with healthy adolescents.

Full description

Polycystic Ovary Syndrome (PCOS) is associated with hyperandrogenism, hyperinsulinemia and insulin resistance starting in the perimenarchal period. Insulin resistance also increases the risk of developing glucose intolerance, type 2 diabetes, hypertension, dyslipidemia and cardiovascular disorders. Studies on adult women with PCOS show that their aerobic capacity is affected. Therefore, in this study; it was aimed to compare the physical and cardiovascular fitness levels of adolescent PCOS patients with healthy adolescents.Total fat and muscle ratios will be measured with the bioelectrical impedance test (BIA) instrument for body composition evaluation of individuals in both groups. Body mass index (BMI), waist/hip and waist/height ratios will be recorded. The level of cardiovascular fitness will be evaluated with the PACER test, which is among the Fitness Gram Test Protocol. For physical fitness level, muscular strength parameter will be evaluated with hand dynamometer and knee extensor muscle strength, and muscular endurance parameter will be evaluated with sit-up and push-up tests. Participants' physical activities will be evaluated with the Adolescent Physical Activity Questionnaire (PAQ-A).The quality of life of individuals with PCOS will be evaluated with the Polycystic Ovary Syndrome Quality of Life-50 Scale.

Enrollment: 44 patients

Sex: Female

Ages: 14 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria of patients :

• Being between the ages of 14-24,
• Collecting Polycystic Syndrome according to Rotherdam,
• Not having had Covid-19.

Exclusion Criteria of the patients :

• Not to be between the ages of 14-24,
• Not showing the symptoms of Polycystic Ovary Syndrome (PCOS),
• Having had Covid-19,
• Having a chronic disease diagnosed other than PCOS,
• Having cognitive impairment that will affect their cooperation with tests.

Healthy group inclusion criteria

• Being a female adolescent between the ages of 14-24,
• Not having been diagnosed with any chronic disease,
• Adolescents with regular menstrual cycles,
• Not taking any medication known to affect hormone, lipid and carbohydrate metabolism,
• Not having clinical signs of hyperandrogenism,
• Not having had Covid-19.

Healthy group exclusion criteria

• Not to be between the ages of 14-24,
• Having a chronic disease,
• Having had Covid-19,
• Having cognitive impairment that will affect their cooperation with tests.

Trial design

44 participants in 2 patient groups

Healthy group

Description:

Healthy adolescents aged 14-24 who have not been diagnosed with any chronic disease

Patient with PCOS group

Description:

Adolescents between the ages of 14-24 diagnosed with Polycystic Ovary Syndrome according to the Rotherdam criteria.