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Aerobic Exercise: A Potential Rescue From the Negative Ramifications of Poor Sleep

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Florida State University

Status

Begins enrollment this month

Conditions

Cardiovascular Health
Sleep

Treatments

Other: Partial Sleep Deprivation

Study type

Interventional

Funder types

Other

Identifiers

NCT06956963
STUDY00006067

Details and patient eligibility

About

The goal of this interventional study is to differentiate the effects of an acute partial sleep deprivation intervention on markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well as overall wellbeing in active vs sedentary individuals. The main aims of the project are:

  • To differentiate the effects of partial sleep deprivation on central hemodynamics (i.e., central blood pressure and arterial stiffness) in active vs sedentary individuals.
  • To differentiate the effects of partial sleep deprivation on physical (i.e., handgrip strength and reactive strength index) and cognitive performance (i.e., reaction time and impulse control) in active vs sedentary individuals.
  • To differentiate the effects of partial sleep deprivation on overall wellbeing (i.e., cardio-autonomic function, inflammation levels, and psychological mood states) in active vs sedentary individuals.

Participants will be divided into two groups based on aerobic activity level - active or sedentary - and assessed for markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well as overall wellbeing before and after three days of normal sleep and three days of partially deprived sleep (i.e., 30% reduction in total time in bed).

Enrollment

30 estimated patients

Sex

All

Ages

18 to 39 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Chronically active (≥150 minutes of moderate- and/or ≥75 minutes of vigorous-intensity aerobic exercise per week for the last 3 months) OR
  • Sedentary (≤60 minutes of aerobic exercise per week for the last 3 months)

Exclusion criteria

  • Chronic, uncontrolled disease (cardiovascular, metabolic)
  • Poor sleep (regularly achieving <7 hours of sleep per night)
  • Musculoskeletal injury in the last 6 months
  • Obese (grade II or higher)
  • Pregnant

Trial design

Primary purpose

Other

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

30 participants in 2 patient groups

Normal Sleep
No Intervention group
Acute Partial Sleep Deprivation
Experimental group
Description:
30% reduction in habitual time in bed
Treatment:
Other: Partial Sleep Deprivation

Trial contacts and locations

1

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Central trial contact

Michael Ormsbee; Brett Cross

Data sourced from clinicaltrials.gov

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