Aerobic Exercise and Covid-19 Survivors With Post-Intensive Care Syndrome (Pics)

Riphah International University

Status: Completed

Conditions: COVID-19; Post Intensive Care Syndrome

Treatments: Other: Aerobic Exercise Training; Other: Home Plan

Study type: Interventional

Funder types: Other

Identifiers

NCT05341648

Rec/01089 Saad Tariq

Details and patient eligibility

About

To investigate the effects of aerobic exercise program on physical activity, aerobic capacity, anxiety& depression in Covid-19 survivors discharged from Intensive Care Unit. There is evidence in the literature that post-intensive case survivors who have been mechanically ventilated will likely experience short- and medium-term consequences in the form of Post Intensive Care Syndrome (PICS).

Full description

The notion that patients surviving intensive care and mechanical ventilation for several weeks can be discharged home without further medical attention is a dangerous illusion. Post-Intensive Care Syndrome and other severe conditions will require not only adequate screening but early rehabilitation and other interventions. So, this focused control trial will contribute particularly to determining the Effects of the Aerobic Exercise Program in Covid-19 Survivors with Post-Intensive Care Syndrome.

Enrollment: 60 patients

Sex: All

Ages: 30 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergo mechanical ventilation in the ICU.
• Recovered from Covid-19 & Discharged from ICU within the past 2 months.
• Hospital Anxiety and Depression Scale (HADS)>8.
• Scale≥ 2 on MRC Dyspnoea Scale.
• Subjects consenting to participate in the study.

Exclusion criteria

• Positive Covid-19 Test.
• COPD and other respiratory diseases.
• Pre-existing psychotic dementia-type illness.
• Acute neurologic diseases (meningitis, ischemic hemorrhagic stroke).
• Patients with chronic systemic disease.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups, including a placebo group

Experimental Group

Experimental group

Description:

Aerobic Training for 3 days/week with 40-70% Intensity for 6 Weeks

Treatment:

Other: Aerobic Exercise Training

Control group

Placebo Comparator group

Description:

Home plan: Positioning, Breathing Exercises, Muscle Relaxation, and Flexibility exercises for 6 weeks

Treatment:

Other: Home Plan