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Aerobic Exercise to Improve Executive Language Function In Older Adults

US Department of Veterans Affairs (VA) logo

US Department of Veterans Affairs (VA)

Status

Completed

Conditions

Aging

Treatments

Behavioral: Aerobic group

Study type

Interventional

Funder types

Other U.S. Federal agency

Identifiers

NCT00979069
E6860-M

Details and patient eligibility

About

The purpose of this study is to see if exercise can improve brain function in older adults

Full description

Recently, considerable attention has been devoted to examining the beneficial relationship between cognition and aerobic exercise in older adults. Specifically, the effects are thought to involve higher order cognitive processes, such as working memory, switching between tasks, and inhibiting irrelevant information, all of which are thought to be sub- served, in part, by the frontal lobes (Colcombe et al., 2006). Importantly, these areas also are most susceptible to age-related decline (Raz, 2000) and are essential resources for language production (Kemper & Sumner, 2001; Murray & Lenz, 2001). However, despite promising cognitive improvement, changes in frontally-mediated executive language functions have been widely ignored. This is unfortunate considering impaired word retrieval compromises communicative effectiveness, leading to frustration, depression, and withdrawal. Perhaps more importantly, communication ineffectiveness, particularly in the elderly, leads to difficulties interacting with health care professionals leading to further health care burdens. Since cognition, and specifically word retrieval difficulties, usually remain untreated, it is important to find treatment strategies for minimizing these deficits. Therefore, the short-term goal and the purpose of this proposal is to examine the potential of aerobic exercise to improve executive language function in older adults.

Enrollment

20 patients

Sex

All

Ages

65 to 89 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Consent of participants' primary health care physicians to participate in the aerobic exercise.
  • Patients must not have participated in any consistent exercise program or experimental study for at least 3 months prior to enrollment.
  • They must be capable of providing informed consent and complying with the trial procedures.

Exclusion criteria

  • Demented as defined by the Modified Mini Mental Status Exam.
  • Unalterable travel schedules.
  • Site accessibility constraints.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

20 participants in 2 patient groups

Aerobic Group
Experimental group
Description:
12 weeks of aerobic exercise 3 times a week
Treatment:
Behavioral: Aerobic group
Control Group
No Intervention group
Description:
No contact control

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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