Aerobic Exercise Training in Pulmonary Arterial Hypertension

Gazi University

Status: Completed

Conditions: Pulmonary Arterial Hypertension

Treatments: Other: Alternative upper extremity exercises; Other: Upper extremity aerobic exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT02371733

Gazi University2

Details and patient eligibility

About

Decreased exercise capacity, peripheral muscle strength and quality of life and increased dyspnea and fatigue perception is prevalent in patients with pulmonary arterial hypertension. It was demonstrated exercise training has beneficial effects in patients with pulmonary arterial hypertension. However, no study investigated the effects of upper extremity aerobic exercise training, therefore effects of upper extremity aerobic exercise training on outcomes in patients with pulmonary arterial hypertension.

Full description

Patients were diagnosed with pulmonary arterial hypertension according to the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of f the European Society of Cardiology (ESC) and European Respiratory Society (ERS). Primary outcome measurement was exercise capacity, secondary outcomes were respiratory and peripheral muscle strength, physical activity, quality of life, fatigue, dyspnea and depression.

Enrollment: 30 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinically stable
• Under standard medication
• Group 1 pulmonary arterial hypertension patients
• Having no exacerbation or infection

Exclusion criteria

• Cognitive disorders
• Orthopedic and neurological problems
• Pneumonia or acute infection
• Stage 4 heart failure
• Having no comorbidity to avoid performing evaluation and training

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups

Training Group

Active Comparator group

Description:

Intervention:Training group will receive upper extremity aerobic exercise training using arm ergometer and breathing exercises.

Treatment:

Other: Upper extremity aerobic exercise training

Control Group

Sham Comparator group

Description:

Sham: Control group will receive alternative upper extremity exercises and breathing exercises.

Treatment:

Other: Alternative upper extremity exercises